Low Dose Naltrexone delivered to door.

Discover the benefits of LDN with LDN Direct

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Frequently Asked Questions

Naltrexone is a medication that was approved in the 1980s by the FDA to treat drug and alcohol addiction.  It works by blocking opioid receptors.  It was found that at much lower doses than those used to treat addiction, it could have a positive effect on the immune system and potentially help relieve symptoms of many common disorders.

To read more about LDN, visit http://www.lowdosenaltrexone.org

Naltrexone is currently only FDA approved for Alcoholism and Opioid Addiction.  However, like many medications, Naltrexone at low doses is used “off-label” for many conditions.

LDN has been reported helpful with:

  • Fibromyalgia/Chronic Fatigue Syndrome
  • Autoimmune conditions (Colitis, Lupus, Rheumatoid Arthritis, etc…)
  • Cancers of many types
  • Infectious diseases (HIV, Lyme, etc…)
  • Anxiety and Depression
  • Osteoarthritis

For a more comprehensive list, visit www.lowdosenaltrexone.org

LDN is taken by mouth – usually either capsule or liquid form. Dosing ranges from 0.5 to 9mg per day. The most common effective dose is 4.5mg, but can vary from person to person. It is recommended to be taken at bedtime, but can also be effective if taken during the day.

Since LDN is a prescription medication, you need a prescription from a licensed medical doctor.  This website allows you to video conference with a medical doctor (or his assistant) and obtain a prescription, if appropriate.  The prescription will need to be sent to a compounding pharmacy of your choice and would be dispensed just like any other medication.

Your prescription will be faxed to the pharmacy of your choice within two business days of your consult. Some pharmacies take an additional two business days to contact patients.

Must be 18 years and older (or 12 and older if accompanied by a parent or guardian)

Video consultation is available to residents of States where our doctors are licensed.

All 50 States
District of Columbia (DC)

Only a medical doctor can diagnose disease.  However, you can do your own research by checking your blood for markers auto-antibodies and other biomarkers.  You can order testing through a Functional Medicine Practitioner – get started by vising our partner site, Root Causes Clinic.

What Patients Say About LDN

"It has helped with pain levels associated with my fibromyalgia. Additionally, it has reduced the pain associated with peripheral neuropathy."
"LDN has increased my immune system. I feel I haven't gotten sick as frequently. My well-being and mood have also improved, and my psoriasis has cleared up."
“I am doing great with this program. I feel more alert the morning after when I take it. My body is not as achy. I notice I have much less sciatica pain, head-aches, and mood swings when taking LDN.”

Our patients are trying LDN already. It could work for you too.

Standard dosing instructions*

Begin with 1.5 mg each evening, approximately 1 hour before bed. Stay at this dose for two weeks. Every two weeks, add a dose of 1.5 mg. Continue adding until you find the maintenance dose that is best suited to you.

Week 1 + 2: 1.5mg daily
Week 3 + 4: 3mg daily
Week 5 + 6: 4.5 mg daily

If you are beginning at a lower dose, the titration schedule remains the same- you increase by your beginning dose every two weeks until you find your optimal dose.

Keeping a symptom journal will help you to find the best dose. On day one, write down your top 3-5 symptoms and rate them on a scale of 1-10. Twice a week while increasing the naltrexone, rate your symptoms. When you find 100% symptom relief OR plateau at symptom relief, you have found your maintenance dose.

If you experience side effects such as nausea, headache, gas, diarrhea, insomnia, heightened anxiety, or vivid dreams or nightmares, they should be mild to moderate and should self-regulate in 3-5 days. If they do don’t go away by day 5, this indicates the 1.5 mg dose is too high for you to start with, and you should halve your dose to 0.75mg. In this case you will titrate more slowly, increasing every two weeks by 0.75 mg. If the only side effects you experience are insomnia or vivid dreams or nightmares, you may switch to taking the LDN during the day rather than at night.

*These highlights are based on default dosing. Actual dosing might differ significantly.